From synthesis of the active substance to the registration of plant protection product

Plant protection products which are environment friendly, more selective and with a new mode of action are welcomed to be placed on the market and used. The reasons for the growing demand for new active substances are among others the withdrawals of the old ones due to new, more strict requirements and problems with resistance of harmful organisms against the existing active substances. The paper mentions selected methods used at present by chemical researchers to make their efforts in the process of inventing new molecules to be used in plant protection more efficient and less cost consuming. The requirements which should be fulfilled after the development of a new active substance to obtain the permission for use in the European Union (so called Annex 1 listing) are presented and discussed as well as the data and formalities demanded to place new plant protection products on the market in one of the member states. The legal requirements are analyzed as well as the time and costs necessary to register the new plant protection product.